About Us
An interdisciplinary research team at Academia Sinica analyzes SARS-CoV-2 whole-genome sequences using data from the Global Initiative on Sharing All Influenza Data (GISAID). Besides recording the rise and fall of past variants, this monitoring network tracks recently emerging variants, so users can follow how each variant spreads in individual countries (or worldwide) and how mutations occur in different viral genes, such as the S gene, which matters most for vaccines. Users can generate trend charts of specific mutation sites for a selected country (or worldwide) and watch time-lapse animations of how mutations change. The website will also publish reports and analyses of the latest viral variants from time to time.
中央研究院跨領域研究團隊根據全球共享流感數據倡議組織（GISAID）資料，對新型冠狀病毒全基因體序列進行分析。此監測網除記錄過往各變異病毒株消長的情形外，並追蹤近期崛起的變異株，可供使用者觀察各病毒變異株在各國（或全球）傳播的情形，及在不同病毒基因（如對疫苗最重要的S基因）上的變異情形。透過此網站，使用者可依需要產生特定變異點在指定國別（或全球）的消長圖，亦可觀賞變異情形的縮時影片。本網站並將不定期提供最新病毒變異情形的報導及分析。
The analyses used in this monitoring network have been published in the following papers: Analysis of genomic distributions of SARS-CoV-2 reveals a dominant strain type with strong allelic associations (Yang et al. PNAS 2020) and Subtyping of major SARS-CoV-2 variants reveals different transmission dynamics based on 10 million genomes (Yang et al. PNAS Nexus 2022). Analysis of more than 200,000 viral genome sequences showed that SARS-CoV-2 variants can be classified into six major types. Type VI began rising rapidly in many countries in February and March 2020, became dominant by April, and accounts for 99% of currently circulating viruses. Since August 2020, many emerging variants have appeared, most of them derived from Type VI. Website: Ling-Jyh Chen (Institute of Information Science) and Yu-Yen Feng (Institute of Statistical Science). Statistical results: Chia-Wei Chen, Yin-Chun Lin, Han-Ni Hsieh and Sung-Lin Tsai (Hsin-Chou Yang's team).
本監測網所用分析已發表於下述論文：Analysis of genomic distributions of SARS-CoV-2 reveals a dominant strain type with strong allelic associations (Yang et al. PNAS 2020) 和 Subtyping of major SARS-CoV-2 variants reveals different transmission dynamics based on 10 million genomes (Yang et al. PNAS Nexus 2022)。經分析二十萬筆以上的病毒基因序列樣本資料發現，新冠病毒的變異株可歸類為六大類型。其中「第六型」自2020年2、3月開始在各國急速竄升，4月已雄霸一方，佔目前流傳病毒類型的99%。從2020年8月起，多種新興變異株竄起，大多從第六型產生。本網站由資訊所陳伶志研究員及統計所馮聿嬿研究助理建置，楊欣洲研究員團隊的陳佳煒、林胤均、謝涵霓、蔡松霖提供統計結果。